SYNTHESIS OF N-(4-(((6-NITROQUINAZOLIN-4- YL)AMINO)METHYL)PHENYL)MORPHOLINE-4-CARBOXAMIDE
Keywords:
quinazoline, organic synthesis, cyclizationAbstract
Quinazolines, as fused bicyclic heterocycles, are of particular importance in organic synthesis and medicinal chemistry. In the present study, the targeted synthesis of a novel compound, N- (4-(((6-nitroquinazolin-4-yl)amino)methyl)phenyl)morpholine-4-carboxamide, was achieved in high yield. This molecule represents a key intermediate for the preparation of 4,6-disubstituted quinazoline derivatives. The structure of the obtained compound was confirmed by modern physicochemical methods, including 1H NMR, 13C NMR, and HRMSReferences
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